Man City vs Man United Prediction: Lineups, Odds & Stats

*Odds are subject to change.

Man City and Man United renew their rivalry in English Premier League (EPL) matchweek four. Pep Guardiola’s men face Ruben Amorim’s cross-city rivals in a key Manchester derby. Kick off is at 4:30 pm on Sunday, 14 September 2025.

Hugely experienced 46-year-old Englishman Anthony Taylor will referee the action.

Match Prediction

Man United have had recent form against City. For that reason, my main prediction is the draw at 4.0 from Betway. Ruben Amorim often plays cautious tactics against the top sides. Despite United’s woes, their defence can look secure in a low block. So the bookies may be overestimating City’s chances.

Or if you fancy a bold bet, Man United to win is 4.33 on Betfred website. Considering their good recent form and the spark of a local derby, this price is tempting. Even more so given City’s patchy confidence this season.

The Latest News for Man City

This latest Man City squad seems inferior to Pep Guardiola’s four-in-a-row title-winning sides. The 2025-26 season sees the Sky Blues still in transition, as they adapt to squad and tactical changes.

City has some injuries to contend with. Mateo Kovacic’s achilles injury is an ongoing issue. While many players carry a knock: Nico O’Reilly, Marcus Bettinelli, Josko Gvardiol and Savinho. Forwards Rayan Cherki (thigh) and Omar Marmoush (knee) are both out. Abdukodir Khusanov (calf) is unlikely to play this Sunday. Yet, Rico Lewis (knock) and John Stones (muscle injury) might be fit enough to start.

City is in a scarcely believable thirteenth place in the EPL table. After their first three matches, they’ve only gained three points. After a gameweek one 4-0 win versus Wolves. Then two consecutive defeats, losing to Tottenham 2-0 and to Brighton 2-1.

Player in Focus

Erling Haaland – City’s powerhouse striker leads the EPL top scorer charts. He has three goals in his first three games this term. Plus, a five-goal haul in Norway’s 11-1 midweek crushing of Moldova. You can back Haaland to score first (4.33 at Coral) as he aims for 2025-26 EPL Golden Boot glory.

The Latest News for Man United

This is a crunch season for Man United. Ruben Amorim has spent over £200 million to re-mould his squad. So there’s no hiding place and the pressure is on at Old Trafford.

The United squad is missing some key players due to Injury. Lisandro Martinez has a long-term knee concern. Mattheus Cunha could miss this game; he picked up a hamstring knock against Burnley last week. Mason Mount is another doubt. He only played 30 minutes of the Burnley match. Diogo Dalot’s muscular injury is likely to sideline him for now.

United are currently in ninth place in the standings. Their goal difference is equal after four goals scored and four against so far. The first three results were mixed together. An opening day defeat to Arsenal, then a 1-1 draw at Fulham. And most recently, a nervy 3-2 home win over Burnley thanks to a last-gasp Bruno Fernandes penalty.

Player in Focus

Bruno Fernandes – The United captain scored 8 EPL goals and provided 11 assists last season. He also takes United’s penalties. So, you can back him to score anytime at odds of 4.20 with Ladbrokes online.

Man City vs Man United Possible Lineups

Man City (4-1-2-3): Gianluigi Donnarumma – Rico Lewis, Ruben Dias, John Stones, Rayan Ait Nouri – Rodri – Tijjani Reijnders, Bernardo Silva – Oscar Bobb, Erling Haaland, Jeremy Doku

Man United (3-4-2-1): Altay Bayindir – Leny Yoro, Matthijs de Ligt, Luke Shaw – Amad Diallo, Casemiro, Kobbie Mainoo, Patrick Dorgu – Bruno Fernandes, Bryan Mbeumo – Benjamin Sesko

Man City vs Man United Head to Head

What do the last 10 meetings between these bitter rivals reveal? City have won four of their last five home matches against United. Scoring 16 goals and conceding 8 times. But those stats do include two huge wins back in 2022.

However, Man Utd have enjoyed recent success against City. Including a 2024 FA Cup Final win and a last gasp 2-1 win in December 2024, after being 1-0 down until 88 minutes.

We also note the last 5 games have seen 12 goals, suggesting City’s dominance in this fixture is waning.

What Channel is Man City vs Man United on?

UK viewers can tune into Sky Sports Main Event or Sky Sports Premier League to see the Manchester derby.