Liverpool vs Everton Prediction: Preview with Lineups & Stats

*Odds are subject to change.

It’s gameweek five of the English Premier League (EPL) 2025-26 season. Anfield will reach fever pitch as Liverpool host Everton in the Merseyside derby. Kick off at Anfield is scheduled for early afternoon, 12:30 pm on Saturday, 20 September 2025.

Experienced referee Darren England is the main match official.

Liverpool vs Everton Prediction

It’s difficult to look past a Liverpool win. They’ve continued this season full of confidence. But the 1.48 with Coral on a home win looks skinny. More value is available on Liverpool -1 handicap. If the Reds win by two clear goals, William Hill will payout at 2.20.

Another wager to look at is the line over 3.5 goals. At 2.50 from Bet365, this could be a good prediction, considering the tempo and action in these local derbies. Liverpool has scored 14 goals in only 4 EPL matches this term. With the fervent Anfield crowd behind them, this could be a high-scoring encounter.

The Latest News for Liverpool

Liverpool is the defending EPL champions and has made a significant investment in their squad. Arne Slot’s men are favourites to win the league – and look as strong as ever.

The Reds have a few injuries in midfield. 20-year-old Stefan Bajcetic remains unavailable for selection with a hamstring issue. Curtis Jones has a muscle injury and may make the squad for Everton’s visit. Alexander Isak is in contention to start. The forward made his Liverpool debut against Atletico Madrid in midweek. Alexis Mac Allister is available after featuring off the bench in that match.

There are no current suspensions in the Liverpool first team squad.

Liverpool top the EPL table with a 100% record from four league games. Their goal difference is already looking healthy, with 9 goals scored and only 4 goals against. The Reds have developed a habit of winning, even when not in top form. The recent 1-0 win over Arsenal laid a marker down in the title race. They kept their perfect record, as Mo Salah struck a 95th-minute penalty at Burnley last Sunday.

Player in Focus

Mo Salah – Already a Liverpool legend, Salah continues to inspire teammates and fans. He seems to pop up with important goals and contributions. He will have plenty of motivation to add to his 2 EPL goals so far this season. Check his anytime goalscorer odds of 2.10 at Betway.

The Latest News for Everton

Since taking the Everton hot seat in January 2025, David Moyes has galvanised The Toffees. Now in his second spell as manager, he’s made some astute transfers already. And the move into the Hill Dickinson Stadium has brought renewed belief.

David Moyes is awaiting news on two injury concerns. Defender Jarrad Branthwaite is yet to appear this term due to a hamstring injury. He may return to fitness in October 2025. Ukrainian left-back Vitalii Mykolenko is 50/50 to play against Liverpool. He picked up a knock in the recent Wolves game.

No players in the Everton squad carry a suspension.

Everton have started the season in fine fettle. Currently sixth in the EPL table, they’ve taken seven points from four matches so far. Last weekend’s 0-0 draw versus Aston Villa stalled a two match winning streak. Having before recorded a 3-2 win over Wolves and a 2-0 triumph against Brighton.

Player in Focus

Jack Grealish – Everton’s decision to take Grealish on loan from Man City looks inspired. He has a point to prove, and he is keen to impress and earn an England international recall. Check out his 7.50 odds at Betway to gain an assist. There’s every chance Grealish can weave his creative magic in this match and help set up a goal.

Liverpool vs Everton Predicted Lineups

Liverpool (4-2-3-1): Alisson Becker – Dominik Szoboszlai, Virgil Van Dijk, Ibrahim Konate, Milos Kerkez – Alexis Mac Allister, Ryan Gravenberch – Florian Wirtz, Cody Gakpo, Mohamed Salah – Hugo Ekitike

Everton (4-2-3-1): Jordan Pickford – Jake O’Brien, James Tarkowski, Michael Keane, James Garner – Tim Iroegbunam, Idrissa Gueye – Jack Grealish, Kiernan Dewsbury-Hall, Iliman Ndiaye – Beto

Liverpool vs Everton: Previous Meetings

Liverpool have won 3 from the last 5 Merseyside derbies, keeping a clean sheet 3 times. 4 of the previous 5 results featured under 2.5 goals.

What Channel is Liverpool vs Everton on?

TNT Sports 1 and TNT Sports Ultimate will broadcast the action live. If you have a TNT Sports subscription, check out the Discovery+ app to watch the game on a mobile device.